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Louisville vs Ole Miss: prediction and projected score

Final: Louisville 38, Ole Miss 41. We projected Ole Miss 31.8-27.7 (61%) โ€” winner called correctly.

Matchup analysis

Before kickoff our model projected Ole Miss 31.8, Louisville 27.7 on a neutral field at Nissan Stadium in Week 1. That is a lean: Ole Miss wins about 61% of the time by our estimate, with a projected margin of 4.1 points and 59.5 combined points. Tags: upset alert, leans high scoring.

Louisville has not played a game yet this season, so its number leans on last year's results. Ole Miss has not played a game yet this season, so its number leans on last year's results.

Louisville's strong offense (20th of 139 in our opponent-adjusted ratings, worth about 33.7 points against an average defense) meets Ole Miss's strong defense (23rd) โ€” an even matchup on paper, so game script and turnovers will decide how many points Louisville puts up. The most lopsided unit battle: Ole Miss's elite offense (6th of 139 in our opponent-adjusted ratings, worth about 38.2 points against an average defense) against Louisville's middle-of-the-pack defense (48th).

College football is noisy: even a well-rated projection misses the final margin by about 14 points on average. Based on how real results have scattered around our numbers, the final margin should land somewhere between Louisville by 18 and Ole Miss by 27 about 80% of the time.

Neutral site, so no home-field points either way. The game is on ABC.

Result: Louisville 38, Ole Miss 41. The model had the right winner; the margin was off by 1.1 points and the total by 19.5.

Market lines

Market lines ยท Source: The Odds API, ESPN, Action Network ยท Updated Oct 29, 9:25 AM UTC. Shown for information; not an input to our projections.

ProviderSpread (open โ†’ now)Total (open โ†’ now)Moneyline (Louisville / Ole Miss)
ConsensusOle Miss -8.5 โ†’ Ole Miss -6.552.5 โ†’ 54.75+215 / -264
BovadaOle Miss -8.5 โ†’ Ole Miss -6.552.5 โ†’ 55+220 / -270
DraftKingsOle Miss -6.554.5+210 / -258

This game's lines: CollegeFootballData.com ยท read Oct 22, 6:37 PM UTC.

ProjectionMarginTotalOle Miss win
Our modelOle Miss -459.561%
Market consensusOle Miss -6.554.870%
Blended projectionOle Miss -655.466%

Blended projection = 0.16 x our margin + 0.84 x the market margin, weights fitted on past seasons (see methodology).

Model vs market

Ole Miss win probability
model 61% ยท market (no-vig) 70% ยท difference -9 pts
Margin
model Ole Miss -4.1 ยท market Ole Miss -6.5 ยท difference -2.4 pts (Ole Miss view)
Total
model 59.5 ยท market 54.75 ยท difference +4.8

Model margin is 2.4 pts more toward Louisville than the market.

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Original projection vs new formula

ProjectionScoreWin probMargin missTotal miss
Original projectionLouisville 27.7, Ole Miss 31.8Ole Miss 61%right winner1.119.5
New formulaLouisville 26.1, Ole Miss 32.2Ole Miss 64%right winner3.120.6

Final: Louisville 38, Ole Miss 41. Original = the number we posted before kickoff. New formula (2026-10-21 matchup terms) = the current model re-run with only the games played before this one.

Louisville vs Ole Miss: stat comparison

2025 season numbers (this season's sample is still too small).

Basic
StatLouisvilleOle Miss
Points per game29.9#4636.9#10
Points allowed per game21.2#3821.1#37
Yards per play6.41#286.86#16
Yards per play allowed4.76#85.45#41
Rushing yards per game178.4#60182.8#50
Net passing yards per game228.8#62317.9#3
Rushing yards allowed per game130.8#21165.9#77
Net passing yards allowed per game173.6#14193.7#34
Turnovers per game1.15#880.87#41
Takeaways per game1.31#350.73#116
Sacks per game2.38#342.13#57
Sacks allowed per game1.85#801.20#18
Advanced
StatLouisvilleOle Miss
EPA per play+0.03#69+0.12#23
EPA per play allowed-0.09#18+0.03#86
Success rate45.3%#3747.8%#16
Success rate allowed36.9%#1640.1%#48
Explosive play rate12.5%#6414.2%#21
Explosive plays allowed10.2%#2711.5%#46
Havoc rate13.5%#4112.0%#82
Havoc allowed12.5%#8410.6%#26
Points per scoring opportunity3.86#794.62#14
Points per opportunity allowed3.74#543.38#17
Average starting field positionown 34#6own 29#103
Opponents' starting field positionown 28#43own 28#28
Offensive plays per game (pace)63.5#10373.0#9
Situational
StatLouisvilleOle Miss
Rushing EPA per play+0.12#20+0.04#65
Passing EPA per play-0.05#101+0.21#16
Rushing EPA allowed-0.02#53+0.12#126
Passing EPA allowed-0.16#18-0.05#42
Rushing success rate50.7%#845.1%#50
Passing success rate41.0%#6850.5%#6
Run stuff rate21.2%#11420.2%#102
Passing-down success rate27.5%#10238.4%#8
Passing-down success allowed23.3%#730.4%#81
Third-down conversion rate38.6%#9343.1%#49
Third-down rate allowed33.5%#1438.5%#50
Red-zone touchdown rate66.7%#3765.3%#45
Red-zone TD rate allowed59.4%#6555.0%#33

# = rank among 136 FBS teams. Efficiency numbers exclude garbage time. Per-play numbers of teams with a weak schedule are pulled toward their opponent-adjusted values (fully at one standard deviation below an average schedule). Source: play-by-play (cfbfastR / sportsdataverse), aggregated by us.

More: Louisville schedule ยท Ole Miss schedule ยท all Week 1 projections

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Projections are statistical estimates for entertainment and analysis only. They are not betting advice and nothing here guarantees any result.

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